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Títol
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CELL |
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Categories
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Autor
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Jane Prophet y Neil Theise |
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Any
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2002 |
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URL
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http://www.janeprophet.com/cell/html/about2.html |
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Descripció breu del projecte
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Cell explora de forma colaborativa la investigación en células madre y la forma en la que ésta redefine la complejidad de la biología humana. |
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Descripció projecte
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Cell is a collaborative projectm that investigates stem cell research.
The collaboration explores how current research into adult stem cells is having to re-address the complexity of human biology. Human cells have been traditionally thought of as behaving in predictable ways. Stem cells can be described as the ‘master’ cells whose off-spring are the more specialised, but limited, cells that make up most of the human body. But current research suggests that at a cellular level the human body behaves in less obvious ways than has been imagined and that adult stem cell activity, which has recently become the focus of widespread attention, may be harder to define, and observe, than previously expected.
This installation is an artistic visualisation of the concept of cell characterisation (irreversible gene restriction) in stem cells. Neil Theise’s theory of a 'Paradigm Shift' in cell behaviour in the human body challenges the notion of irreversibility. The model of the paradigm shift has been simplified for exhibition in dialogue between Theise and Jane Prophet.
The model is a real-time 2D graphic interpretation using a complex system of multiple moving 'agents' generated through artificial life (A-life) programming.
The 'old' paradigm of stem cell behaviour was that stem cell development/replication was irreversible and progressive and that after a certain number of replications cells were therefore no longer plastic (functionality was irretrievably switched off). This irreversible gene restriction is indicated by shifts in the colour of 'cells'.
In this graphic simulation cells in the human body are represented as coloured discs (with four chromosomes) emanating (being 'produced') from a set location in the centre of a 2D window. Cells start at the centre of screen and move towards the periphery, by the time they reach the periphery they die. When stem cells are first 'born' they are white in colour indicating their high level of plasticity (many genes are switched on)and a hue is generated for each cell that mutates when it differentiates. The brightness and saturation of the colours displayed are based on each cell's hue; the brightness of the colour decreases with each generation, to a minimum brightness of 50% at death; and the saturation depends upon how differentiated the cell is.
To prevent runaway population explosions the population of cells is cleared and begins again when the number of cells reaches 500.
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Desripció tècnica
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As part of the collaboration, medical scientist Dr Neil Theise, a world leader into adult stem cell research, based in New York, has been working together with Jane Prophet, mathematician Mark d’Inverno, computer scientist Rob Saunders and curator Peter Ride, who instigated the project, from the University of Westminster. One aim has been to find new ways of visualising the new and contentious theories of stem cell behaviour, and to find ways to feed the visualisation back into the scientific research so that it can be a conceptual tool in the laboratory practice. Another has been to generate a range of artistic outcomes that are under-pinned by the emerging understanding of cellular activity.
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Comentaris
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Ciutat
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país
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UK |
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Paraules clau
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Revisat per
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bello bugallo, mónica |
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